Textbook in PDF format This book presents the state-of-the-art and breakthrough innovations in design automation for cyber-physical systems.The authors discuss various aspects of cyber-physical systems design, including modeling, co-design, optimization, tools, formal methods, validation, verification, and case studies. Coverage includes a survey of the various existing cyber-physical systems functional design methodologies and related tools will provide the reader unique insights into the conceptual design of cyber-physical systems. Front Matter Concept Design: Modeling and Synthesis from Requirements to Functional Models and Simulation Platform-Based Design for Automotive and Transportation Cyber-Physical Systems An Hourglass-Shaped Architecture for Model-Based Development of Networked Cyber-Physical Systems Front Matter Formal Techniques for Verification and Testing of Cyber-Physical Systems Data-Driven Safety Verification of Complex Cyber-Physical Systems System Assurance in the Design of Resilient Cyber-Physical Systems Front Matter Optimal Design of Distributed Controllers for Large-Scale Cyber-Physical Systems Model-Driven Software Design Automation for Complex Rehabilitation Design Automation Using Structural Graph Convolutional Neural Networks Design Automation for Energy Storage Systems Back Matter