Textbook in PDF format This book presents a comprehensive, practitioner-focused framework for applying Lean Six Sigma (LSS) within the chemical and pharmaceutical process industries—sectors that have historically been underserved by mainstream LSS literature. While most existing resources concentrate on discrete manufacturing, this work addresses the distinct challenges of process-driven environments, including complex batch operations, stringent regulatory requirements, and variability in raw materials and formulations. By adapting core LSS tools, such as DMAIC, SMED, Heijunka, and Visual Management, to these realities, the book provides a practical roadmap for achieving operational excellence where precision, compliance, and adaptability are essential