Textbook in PDF format The rhizosphere is a zone of intense biological and chemical activity, which plays a critical role in shaping plant growth, nutrient uptake, and ecosystem functioning. Recent advances in our understanding of root signaling and rhizosphere engineering have revealed the vast potential for manipulating these interactions to enhance crop productivity, improve soil health, and mitigate environmental stresses. It is worthwhile to decipher the molecular signals and nutrient exchanges between plants and microbes, which can in turn facilitate to design an innovative strategy to optimize rhizosphere functioning